Insulin Keeps PYK-ing on eNOS
نویسندگان
چکیده
منابع مشابه
Insulin Keeps PYK-ing on eNOS: Enhanced Insulin Receptor Signaling Induces Endothelial Dysfunction.
may subscribe for their personal use at the following rates for print subscriptions: $225 for AHA/ASA Domestic and International Members (excluding General Membership level), or $790 for domestic non-members and $937 for international non-members. AHA membership information can be found online at professional.heart.org. Periodicals postage paid at Hagerstown, MD, and additional mailing offices.
متن کاملInsulin keeps time
VASP comet sightings ess is more when it comes to actin-fueled propulsion. Julie Plastino, Stéphane Olivier, and Cécile Sykes (Institut Curie, Paris, France) show that hollow actin comets propel beads faster than a more filament-packed comet. Actin comets, which drive bead or bacteria movement, are thought to depend strongly on Arp2/3–built, branched actin networks. Now, Plastino et al. show th...
متن کاملMultiple signaling pathways in flow-mediated endothelial mechanotransduction: PYK-ing the right location.
The endothelial monolayer is a signal transduction interface for blood-borne mechanical as well as chemical stimuli. The structural deformation arising from a mechanical stimulus, such as a change of hemodynamic shear stress, is conceptually different from the binding of a hormone or other agonist to its specific receptor, yet both elicit important endothelial signaling responses. Mechanical an...
متن کاملMUNC-ing around with insulin action.
Defective uptake of glucose into muscle and fat cells, or insulin resistance, is a central feature of obesity and type 2 diabetes. As we brace ourselves for the diabetes epidemic, it is reassuring to know that real progress is being made in defining the molecular biology of how insulin stimulates glucose uptake and what goes awry in obesity and type 2 diabetes. An understanding of the molecular...
متن کاملPyk 2 and Fak In
1. Abstract 2. Introduction 3. Discussion 3.1. Integrins and Osteoclasts 3.1.1. Mechanism of Osteoclastic Bone Resorption 3.1.2. Integrin alphavbeta3 is Involved in Regulating Osteoclastic Bone Resorption 3.2. PYK2 in Osteoclasts 3.2.1. Functional Expression of PYK2 in Osteoclasts 3.2.2. PYK2 in Integrin alphavbeta3-mediated Signaling in Osteoclasts 3.3. FAK in Osteoclasts 3.3.1. Functional Exp...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Circulation Research
سال: 2017
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.117.310576